Apa itu six sigma pdf

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The discovery of heparin was announced in 1916. In the United States it costs about 25 to 50 USD per month. In therapeutic doses, it acts as an anticoagulant, preventing the formation of clots and extension of existing clots within the blood. This condition is usually reversed on discontinuation, and in general can be avoided with the use of synthetic heparins. Also, a benign form of thrombocytopenia is associated with early heparin use, which resolves without stopping heparin. Two non-hemorrhagic side-effects of heparin treatment are known. This abnormality is not associated with liver dysfunction, and it disappears after the drug is discontinued.